The Carb-Insulin Hypothesis vs Protein Leverage Hypothesis of Obesity

I’ve recently been having some ‘robust discussion’ on social media around what I think amounts to the Carb-Insulin Model vs the Protein Leverage Hypothesis of obesity and diabetes.  I wanted to unpack and juxtapose the similarities and differences between the two models and explain why I feel the protein leverage hypothesis is a more elegant, …

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Keto Lie #4: Protein Should Be Avoided Due to Gluconeogenesis

Perhaps the biggest differentiator between keto and other successful versions of a lower-carb diet like Atkins, Paleo, Bernstein, Banting, and Carnivore is the misguided fear that ‘excess protein’ keeps ketones low and insulin high through the process of gluconeogenesis. Ever since Jimmy Moore broadcasted the idea that protein could convert to sugar via gluconeogenesis and, …

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Protein Leverage | Professors Stephen Simpson and David Raubenheimer

University of Sydney Professors Stephen Simpson and David Raubenheimer’s work in protein leverage is perhaps the most important body of research around, empowering us to understand our appetite and what leads us to eat more (or less) than we need to.   Professor Stephen Simpson is the executive director of Obesity Australia and the academic director …

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Does Too Much Protein Accelerate Aging?

Professors Stephen Simpson and David Raubenheimer have identified what appears to be the universal explanation for obesity – the Protein Leverage Hypothesis. The Protein Leverage Hypothesis demonstrates how our appetite for protein will drive excess energy intake and, consequently, obesity when the proportion of protein in our diet is low. However, counterintuitively, they also caution …

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